Was randomly reading online about genetic predisposition to various cat diseases and found this: "YEAST INFECTIONS OF SKIN (MALASSEZIA DERMATITIS) Type: genetic link possible Breeds: Devon Rex Fungal infection of the nail beds; possible genetic predisposition due to excessive sebum or poor immune response towards the yeast. Colombo et al (2007) found Malassezia in 100% of Devon Rex cats studied compared to 42% of Persians and randombred shorthairs studied." So we all know, Sphynx come from Devon Rex and thus can have similar genetic issues. Over the years on the lair we have discussed Sphynx getting yeast infections in the nail bed area if not cleaned regularly, but I dont think any of us have known why it happens. Ive always assumed it was their excessively fleshy toes/skin folds. In laymens terms, this says genetically, devon rex either might make more skin oils OR their immune system leaves them susceptible to yest infections. Pretty interesting!